منابع مشابه
Protamines. Isolation, characterization, structure and function.
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متن کاملAllelic Expression of Drosophila Protamines during Spermatogenesis
In typical somatic cells, DNA is tightly organized by histones that are necessary for its proper packaging into the nucleus. In sexually-reproducing animals, the haploid product of male meiosis must be further condensed to fit within sperm heads, thus requiring an even greater degree of packaging. This is accomplished in most organisms by replacing histones with protamines, which allows DNA to ...
متن کاملProtamines: structural complexity, evolution and chromatin patterning.
Despite their relatively arginine-rich composition, protamines exhibit a high degree of structural variation. Indeed, the primary structure of these histone H1-related sperm nuclear basic proteins (SNBPs) is not random and is the depository of important phylogenetic information. This appears to be the result of their fast rate of evolution driven by positive selection. The way by which the prot...
متن کاملInhibitory effects of protamines on proteolytic and adhesive activities of Porphyromonas gingivalis.
Protamines (salmine prepared from sperm DNA of salmon and clupeine from herring sperm), which are basic peptides rich in arginine, were found to inhibit the proteolytic activity of arginine-specific cysteine protease (RC-protease) from Porphyromonas gingivalis. Lineweaver-Burk plot analysis revealed that the protamines competitively inhibited proteolytic activity with cleavage of benzoyl-L-argi...
متن کاملProtamines, in the footsteps of linker histone evolution.
It was perhaps a lucky coincidence that the early attempts to establish the chemical composition of the cell nucleus were initially carried out on such diverse biological systems as salmon sperm heads (1) and geese and chicken erythrocytes (2). Examination of sperm and erythrocyte systems, respectively, lead to the protamine and histone concepts (3). We know with certainty that, with the except...
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ژورنال
عنوان ژورنال: The Journal of Biochemistry
سال: 1972
ISSN: 1756-2651,0021-924X
DOI: 10.1093/oxfordjournals.jbchem.a130036